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MPP top tier targets

Investigator:David Pagliarinipagliarini@wisc.edu Lead protein purification group:none
Primary contact:none Lead spectroscopist:none
Project manager:John Everetteverett.jk@gmail.com Lead crystallographer:none

Project description


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  page 1 / 1 pages   (102 targets)       Sort method         group child targets


rank    target id target         PDB homology status last record time since last record experimentalist
1. (6) (2/13) 23 HR6839C MTHFD2  crystal hits2013-12-17 aggregation screening 3 years, 10 days
2. (4) (0/0) 23 HR6839A MTHFD2  soluble construct2012-12-05 expression [3, 0] ...4 years, 22 days
3. (6) (0/0) 23 HR6839B MTHFD2  soluble construct2012-12-05 expression [0, 0] ...4 years, 22 days
4. (3) (0/0) 23 HR6839 MTHFD2  selected2010-09-21 target created7 years, 3 days
5. (4) (9/13) 27 HR9254A SLIRP  good HSQC collected2014-04-28 HSQC [not scored] ...3 years, 28 days
6. (5) (4/6) 27 HR9254 SLIRP  HSQC collected2013-09-18 expression [4, 5] ...4 years, 5 days
7. (2) (0/0) 27 HR9254B SLIRP  expression tested2013-01-18 expression [0, 0] ...4 years, 8 days
8. (12) (1/1) 6 HR6550A C20orf7  HSQC collected2014-02-11 purification [0.0 mg]3 years, 14 days
9. (11) (1/3) 6 HR6550 C20ORF7  aggregation screening2014-04-30 expression [3, 0]3 years, 26 days
10. (3) (0/0) 6 HR6550B C20orf7  selected2011-07-25 target created6 years, 1 day
11. (6) (1/1) 21 HR2478B ACAD9  aggregation screening2013-01-15 expression [0, 0] ...4 years, 11 days
12. (4) (1/1) 21 HR2478A ACAD9  purified2014-04-23 expression [4, 5]3 years, 3 days
13. (4) (1/1) 21 HR2478 ACAD9  purified2012-11-14 purification [4.7 mg]4 years, 13 days
14. (4) (0/0) 21 HR2478C ACAD9  expressed2012-11-29 expression [0, 0] ...4 years, 28 days
15. (26) (1/3) 16 HR5037 ADCK1  aggregation screening2013-11-05 expression [0, 0] ...3 years, 22 days
16. (3) (0/0) 16 HR5037A ADCK1  fermented with good ES score2014-04-23 expression [5, 5]3 years, 3 days
17. (2) (0/0) 16 HR5037B ADCK1  selected2011-07-25 target created6 years, 1 day
18. (20) (0/1) 12 YR217 ABC1  aggregation screening2014-07-23 aggregation screening 3 years, 2 days
19. (2) (0/0) 12 YR217B ABC1  soluble construct2011-02-04 expression [5, 0] ...6 years, 22 days
20. (3) (0/0) 12 YR217C ABC1  expressed2011-02-04 expression [0, 0] ...6 years, 22 days
21. (6) (0/0) 12 YR217A ABC1  expression tested2011-02-04 expression [0, 0] ...6 years, 22 days
22. (19) (0/0) 12 YR217D ABC1  selected2011-07-25 target created6 years, 1 day
23. (20) (0/0) 12 YR217E ABC1  selected2011-07-25 target created6 years, 1 day
24. (2) (1/2) 11 ER593 UBIB  purified2011-06-20 purification [15.2 mg] ...6 years, 6 days
25. (2) (0/0) 11 ER593A UBIB  expressed2011-02-04 expression [0, 0] ...6 years, 22 days
26. (1) (0/0) 41 HR1086 METTL8  purified2003-05-02 expression [5, 0] ...14 years, 27 days
27. (10) (0/0) 26 HR2114 PRO1853  purified2013-11-05 expression [0, 0] ...3 years, 22 days
28. (2) (0/0) 26 HR2114A LRPPRC  expressed2012-10-15 expression [0, 0] ...4 years, 13 days
29. (4) (1/1) 8 HR2475A NDUFAF2  purified2013-02-06 purification [2.0 mg]4 years, 19 days



       PDB seq homology

   
HR2475A-1-83-15.*

   
HR2475A-1-83-Av6HT.*

   
HR2475A-1-104-15.*

   
HR2475A-1-104-Av6HT.*




rank target id target PDB homology status last record time since last record experimentalist
30. (2) (0/0) 8 HR2475 NDUFAF2  purified2012-11-15 purification [0.0 mg]4 years, 12 days
31. (3) (0/1) 2 HR3082 BLOC1S1  purified2013-09-18 purification [2.8 mg] ...4 years, 5 days
32. (1) (0/0) 2 HR3082B BLOC1S1  expression tested2010-11-10 expression [0, 0] ...6 years, 18 days
33. (1) (0/0) 2 HR3082A BLOC1S1  expression tested2009-01-07 expression [0, 0] ...8 years, 20 days
34. (5) (1/1) 1 HR3311A COQ4  purified2014-04-23 expression [3, 5]3 years, 3 days
35. (8) (0/0) 1 HR3311 COQ4  soluble construct with excellent ES score2013-05-07 expression [5, 5] ...4 years, 19 days
36. (20) (0/0) 18 HR4883 ADCK4  purified2014-06-26 purification [0.0 mg]3 years, 29 days
37. (5) (0/0) 18 HR4883A ADCK4  purified2012-12-03 purification [0.0 mg] ...4 years, 24 days
38. (17) (0/0) 18 HR4883C ADCK4  expressed2012-12-05 expression [0, 0] ...4 years, 22 days
39. (11) (0/0) 18 HR4883B ADCK4  selected2011-07-25 target created6 years, 1 day
40. (12) (0/0) 7 HR5069 ADCK2  purified2013-11-05 expression [0, 0] ...3 years, 22 days
41. (4) (0/0) 7 HR5069A ADCK2  soluble construct2012-12-05 expression [0, 0] ...4 years, 22 days
42. (4) (0/0) 7 HR5069B ADCK2  expressed2012-12-05 expression [0, 0] ...4 years, 22 days
43. (3) (0/0) 22 HR5400 C1ORF166  purified2013-10-18 purification [18.5 mg]3 years, 10 days
44. (1) (0/0) 22 HR5400A MUL1  expressed2012-06-22 expression [3, 0] ...5 years, 3 days
45. (2) (0/0) 22 HR5400B MUL1  expression tested2012-06-22 expression [0, 0] ...5 years, 3 days
46. (2) (2/2) 24 HR6071 DIP2  purified2014-01-10 purification [17.4 mg]3 years, 16 days
47. (6) (0/1) 19 HR6597A COQ7  purified2014-04-30 expression [2, 0]3 years, 26 days
48. (7) (0/0) 19 HR6597 COQ7  fermented with good ES score2014-04-23 expression [1, 5] ...3 years, 3 days
49. (5) (0/0) 15 HR6609 PPTC7  purified2013-01-16 purification [12.0 mg]4 years, 10 days
50. (5) (0/0) 15 HR6609A PPTC7  expression tested2011-03-08 expression [0, 0] ...6 years, 20 days
51. (6) (1/1) 3 HR6626 LACTB  purified2014-02-10 purification [0.0 mg]3 years, 15 days
52. (2) (0/0) 3 HR6626A LACTB  expression tested2011-03-08 expression [0, 0] ...6 years, 20 days
53. (6) (0/0) 20 HR6649A NDUFAF3  purified2014-04-30 expression [2, 0]3 years, 26 days
54. (6) (0/0) 20 HR6649 NDUFAF3  purified2013-10-18 purification [21.0 mg]3 years, 10 days
55. (5) (0/0) 17 HR6756 FOXRED1  purified2012-12-05 expression [0, 0] ...4 years, 22 days
56. (2) (0/0) 17 HR6756B FOXRED1  fermented with good ES score2014-01-22 expression [4, 3]3 years, 4 days
57. (2) (0/0) 17 HR6756A FOXRED1  expressed2011-07-27 expression [3, 0] ...6 years, 29 days
58. (7) (1/1) 34 HR823 LYRM4  purified2014-04-30 expression [2, 0]3 years, 26 days
59. (9) (4/4) 9 HR9310 PRELID1  purified2014-02-26 purification [0.0 mg] ...3 years, 29 days
60. (2) (1/1) 32 HR9339 THNSL1  purified2014-07-01 purification [0.0 mg]3 years, 24 days
61. (11) (0/0) 14 YR207 YPL109C  purified2013-11-05 expression [0, 0] ...3 years, 22 days
62. (1) (0/0) 14 YR207A YPL109C  selected2010-08-25 target created7 years, 1 month, 0 days
63. (8) (1/1) 28 YR343 SDH1  purified2014-03-14 purification [0.0 mg]3 years, 13 days
64. (4) (0/0) 28 YR343C SDH1  soluble construct with good ES score2013-02-15 expression [2, 4] ...4 years, 10 days
65. (3) (0/0) 28 YR343A SDH1  expressed2013-02-15 expression [3, 0] ...4 years, 10 days
66. (4) (0/0) 28 YR343B SDH1  expressed2013-02-15 expression [0, 0] ...4 years, 10 days
67. (2) (0/0) 39 HR3062C FASTK  purification attempted2010-09-15 expression [5, 0]7 years, 9 days
68. (4) (0/0) 39 HR3062 FASTK  expressed2011-07-22 expression [0, 0] ...6 years, 4 days
69. (1) (0/0) 39 HR3062B FASTK  expressed2009-07-15 expression [3, 0] ...8 years, 11 days
70. (2) (0/0) 39 HR3062A FASTK  expressed2009-07-15 expression [2, 0] ...8 years, 11 days
71. (2) (0/0) 39 HR3062D FASTK  expression tested2009-07-15 expression [0, 0] ...8 years, 11 days
72. (22) (0/0) 4 YR175 YLR253W  purification attempted2014-04-09 expression [2, 5]3 years, 17 days
73. (2) (0/0) 4 YR175A YLR253W  expressed2011-02-04 expression [0, 0] ...6 years, 22 days
74. (6) (0/0) 4 YR175B YLR253W  selected2011-07-25 target created6 years, 1 day
75. (2) (0/0) 10 HR1843 C18ORF43  fermented with good ES score2014-03-12 expression [5, 5]3 years, 15 days
76. (11) (0/0) 5 HR6549 C8ORF38  fermented with good ES score2013-11-05 expression [0, 0] ...3 years, 22 days
77. (8) (0/0) 5 HR6549A C8orf38  fermented with good ES score2014-04-23 expression [4, 5]3 years, 3 days
78. (3) (0/0) 13 HR6551A ADCK5  fermented with good ES score2014-04-23 expression [4, 5]3 years, 3 days
79. (22) (0/0) 13 HR6551 ADCK5  soluble construct2013-11-05 expression [4, 1] ...3 years, 22 days
80. (16) (0/0) 13 HR6551B ADCK5  selected2011-07-25 target created6 years, 1 day
81. (4) (0/0) 37 HR6575 PRELID2  fermented with good ES score2014-03-12 expression [3, 5]3 years, 15 days
82. (5) (0/0) 38 HR6615 BDH1  fermented with good ES score2014-03-12 expression [5, 5]3 years, 15 days
83. (7) (0/0) 30 HR6621 LYRM7  fermented with good ES score2013-11-05 expression [0, 0] ...3 years, 22 days
84. (5) (0/0) 35 HR6757 LYRM2  fermented with good ES score2014-03-12 expression [2, 5]3 years, 15 days
85. (4) (0/0) 33 HR9340 NSUN3  fermented with good ES score2014-03-12 expression [5, 4]3 years, 15 days
86. (4) (0/0) 48 HR124 NIPSNAP10soluble construct with excellent ES score2013-12-05 expression [5, 4] ...2 years, 29 days
87. (10) (0/0) 36 HR2584 C20ORF450soluble construct with excellent ES score2013-12-05 expression [5, 5] ...2 years, 29 days
88. (6) (0/0) 44 HR6606 HSPC268  soluble construct with excellent ES score2013-12-05 expression [2, 3] ...3 years, 22 days
89. (9) (0/0) 43 HR9342 GBAS  soluble construct with excellent ES score2013-12-05 expression [0, 0] ...3 years, 22 days
90. (5) (0/0) 46 HR9344 WBSCR16  soluble construct with excellent ES score2013-12-05 expression [5, 5] ...3 years, 22 days
91. (6) (0/0) 47 HR9345 OXR1_HUMAN  soluble construct with excellent ES score2013-12-05 expression [3, 3] ...3 years, 22 days
92. (4) (0/0) 49 HR9346 C6orf57  soluble construct with excellent ES score2013-12-05 expression [5, 5] ...3 years, 22 days
93. (3) (0/0) 40 HR981 FASTKD20soluble construct with excellent ES score2013-12-05 expression [5, 5] ...2 years, 29 days
94. (3) (0/0) 52 HR6688 ATAD1  soluble construct with good ES score2013-12-05 expression [3, 2] ...3 years, 22 days
95. (3) (0/0) 31 HR6753 LYRM1  soluble construct with good ES score2013-12-05 expression [3, 4] ...3 years, 22 days
96. (7) (0/0) 29 HR8477 COX10  soluble construct with good ES score2013-11-05 expression [2, 1] ...3 years, 22 days
97. (6) (0/0) 29 HR8477C COX10  expressed2012-11-29 expression [0, 0] ...4 years, 28 days
98. (2) (0/0) 29 HR8477B COX10  expressed2012-11-29 expression [0, 0] ...4 years, 28 days
99. (4) (0/0) 29 HR8477A COX10  expression tested2012-12-05 expression [0, 0] ...4 years, 22 days
100. (4) (0/0) 42 HR9341 PREPL  soluble construct with good ES score2013-12-05 expression [3, 4] ...3 years, 22 days
101. (1) (0/0) 50 HR9347 FSIP2  soluble construct with good ES score2013-12-05 expression [4, 3] ...3 years, 22 days
102. (4) (0/0) 45 HR9343 C3orf23  expression tested2013-12-05 expression [0, 0] ...3 years, 22 days