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HR3066A   (UNC119)

3 targets assoicated with this target.
HR3066parentexpression tested
HR3066Csibling(66-240)expressed
HR3066Bsibling(61-240)expressed

database refs UniProt: Q13432 (U119A_HUMAN)   |   HUGO: UNC119   |   NCBI gene: 9094   |   refSeq: NP_005139.1; NP_473376.1
status X-Ray structure
structures 3GQQ (Xray)  
properties length: 185 aa   |   mass: 21.79 kD   |   pI: 6.58   |   ext: 13410   |   organism: Homo sapiens
classes PSI-2, Biomedical: Cancer BioNet T1 (Rutgers), Community Outreach, MEGA, Tech Development: Core 50 PSI-2, Biomedical: Cancer BioNet, BioMedical, PSI-Biology
projects HCPIN    
best PDB match calculating ...
informatics Prof PHD data   |   Zn binding sites: no sites identified. CH type (data) CHDE type (data)
domain signaturesPF05351 details   81296 details   2.70.50.40 details   BINDING:Lipid details  
subsequence details   ie 100-200    
BLAST searches

Construct coverage schematic
Display constructs only from this target (HR3066A).
Display constructs associated with this target (HR3066A) and all other associated targets (HR3066, HR3066C, HR3066B).


Domain and UniProt Features
    CATH 2.70.50.40
    SuperFamily 81296
    PFAM PF05351
    UniProt BINDING:Lipid
    Binding - Lipid domain_number-1


NESG targets
    HR3066A
    HR3066B
    HR3066C

HR3066

       PDB seq homology



Constructs and Most Advanced Status
   
HR3066-15.*

   
HR3066-21.*

   
HR3066A-14.*

   
HR3066B-14.*

   
HR3066C-14.*



most recent record
8 years, 5 days ago --     X-Ray structure: 3gqq

2006-03-15    target: HR3066A
2008-10-16    construct: HR3066A-14.1
2008-12-02    expression [ 4, 4 ] : HR3066A-14.1-ss
2008-12-09    expression [ 5, 2 ] : HR3066A-14.1-SeMa
2008-12-17    purification [16.4 mg]: HR3066A-14.1-SeMa-GF
2009-01-06     aggregation screening [dimer,48.09 kD,84.0%]
2008-12-19     HR3066A.001 @ Columbia; 1.05 ml at 8.48 mg/mL
2009-03-24     X-Ray structure: 3gqq (PDB)
2008-12-19     HR3066A.002 @ HWI; 0.45 ml at 8.48 mg/mL
2008-10-16    construct: HR3066A-14.2
2008-12-02    expression [ 5, 4 ] : HR3066A-14.2-ss


Available samples:

SeMet samples
HR3066A.002 @ HWI HR3066A.001 @ Columbia