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HR3646   (ITSN1)

7 targets assoicated with this target.
HR3646Achild(1-181)selected
HR3646Dchild(1582-1721)selected
HR3646Cchild(701-1228)selected
HR3646Bchild(193-293)selected
HR3646Fchild(1589-1721)expression tested
HR3646Gchild(1153-1228)good HSQC collected and crystal hits
HR3646Echild(1-111)NMR and X-Ray structures

database refs UniProt: Q15811 (ITSN1_HUMAN)   |   HUGO: ITSN1   |   NCBI gene: 6453   |   refSeq: NP_001001132.1; NP_003015.2
status selected
properties length: 1721 aa   |   mass: 195.42 kD   |   pI: 7.76   |   ext: 208210   |   organism: Homo sapiens
classes PSI-2, Biomedical: Cancer BioNet T2 (Rutgers), Biomedical: Cancer BioNet, PSI-Biology
projects HCPIN    
best PDB match calculating ...
informatics Zn binding sites: Analysis not performed.
domain signaturesDOMAIN:SH3 1 details   1.10.238.10 details   DOMAIN:SH3 4 details   PF00621 details   2.30.30.40 details   DOMAIN:EF-hand 2 details   DOMAIN:C2 details   CA_BIND:1 (Potential) details   PF00018 details   DOMAIN:SH3 2 details   DOMAIN:PH details   CA_BIND:2 (Potential) details   PF07653 details   48065 details   DOMAIN:EF-hand 1 details   DOMAIN:SH3 3 details   DOMAIN:DH details   50044 details   1.20.900.10 details   DOMAIN:EH 1 details   DOMAIN:EH 2 details   DOMAIN:SH3 5 details   47473 details   PF12763 details  
subsequence details   ie 100-200    
BLAST searches

Construct coverage schematic
There are no constructs associated with this target (HR3646).
However there are constructs associated with other targets associated with this target (below).

Domain and UniProt Features
    UniProt DOMAIN:EH 1
    EH 1. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:EF-hand 1
    EF-hand 1. {ECO:0000255|PROSITE- domain_number-1
    Ca binding - 1. {ECO:0000255|PROSITE- domain_number-1
    UniProt CA_BIND:1 (Potential)
    CATH 1.10.238.10
    SuperFamily 47473
    PFAM PF12763
    UniProt DOMAIN:EH 2
    EH 2. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:EF-hand 2
    EF-hand 2. {ECO:0000255|PROSITE- domain_number-1
    UniProt CA_BIND:2 (Potential)
    Ca binding - 2. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:SH3 1
    SH3 1. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:SH3 2
    SH3 2. {ECO:0000255|PROSITE- domain_number-1
    SuperFamily 50044
    CATH 2.30.30.40
    UniProt DOMAIN:SH3 3
    SH3 3. {ECO:0000255|PROSITE- domain_number-1
    PFAM PF07653
    CATH 2.30.30.40
    SuperFamily 50044
    SH3 4. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:SH3 4
    PFAM PF07653
    SuperFamily 50044
    CATH 2.30.30.40
    SH3 5. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:SH3 5
    PFAM PF00018
    SuperFamily 48065
    CATH 1.20.900.10
    DH. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:DH
    PFAM PF00621
    PH. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:PH
    C2. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:C2


NESG targets
    HR3646A
    HR3646E
    HR3646B
    HR3646C
    HR3646G
    HR3646D
    HR3646F

HR3646

       PDB seq homology



Constructs and Most Advanced Status
   
HR3646E-Av6HT.*

   
HR3646E-14.*

   
HR3646E-AVMBPB2.*

   
HR3646E-AvMBPB2.*

   
HR3646E-AvSUMO.*

   
HR3646E-SGCAv.*

   
HR3646E-15.*

   
HR3646G-1148-1233-14.*

   
HR3646G-1153-1228-14.*

   
HR3646F-1584-1721-14.*

   
HR3646F-1589-1721-14.*



most recent record
7 years, 4 days ago --     target created

2010-01-25    target: HR3646