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HR3646B   (ITSN1)

7 targets assoicated with this target.
HR3646parentselected
HR3646Asibling(1-181)selected
HR3646Dsibling(1582-1721)selected
HR3646Csibling(701-1228)selected
HR3646Fsibling(1589-1721)expression tested
HR3646Gsibling(1153-1228)good HSQC collected and crystal hits
HR3646Esibling(1-111)NMR and X-Ray structures

database refs UniProt: Q15811 (ITSN1_HUMAN)   |   HUGO: ITSN1   |   NCBI gene: 6453   |   refSeq: NP_001001132.1; NP_003015.2
status selected    work stopped (2010-06-30; End of PSI-2)
properties length: 101 aa   |   mass: 11.18 kD   |   pI: 6.29   |   ext: 12490   |   organism: Homo sapiens
classes PSI-2, Biomedical: Cancer BioNet T2 (Rutgers), MEGA, Biomedical: Cancer BioNet, BioMedical, PSI-Biology
projects HCPIN    
best PDB match calculating ...
informatics Prof PHD data   |   Pxs: 0.152   |   Zn binding sites: Analysis not performed.
domain signatures1.10.238.10 details   CA_BIND:2 (Potential) details   47473 details   DOMAIN:EF-hand 2 details   PF12763 details  
subsequence details   ie 100-200    
BLAST searches

Construct coverage schematic
There are no constructs associated with this target (HR3646B).
However there are constructs associated with other targets associated with this target (below).

Domain and UniProt Features
    UniProt DOMAIN:EH 1
    EH 1. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:EF-hand 1
    EF-hand 1. {ECO:0000255|PROSITE- domain_number-1
    Ca binding - 1. {ECO:0000255|PROSITE- domain_number-1
    UniProt CA_BIND:1 (Potential)
    CATH 1.10.238.10
    SuperFamily 47473
    PFAM PF12763
    UniProt DOMAIN:EH 2
    EH 2. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:EF-hand 2
    EF-hand 2. {ECO:0000255|PROSITE- domain_number-1
    UniProt CA_BIND:2 (Potential)
    Ca binding - 2. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:SH3 1
    SH3 1. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:SH3 2
    SH3 2. {ECO:0000255|PROSITE- domain_number-1
    SuperFamily 50044
    CATH 2.30.30.40
    UniProt DOMAIN:SH3 3
    SH3 3. {ECO:0000255|PROSITE- domain_number-1
    PFAM PF07653
    CATH 2.30.30.40
    SuperFamily 50044
    SH3 4. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:SH3 4
    PFAM PF07653
    SuperFamily 50044
    CATH 2.30.30.40
    SH3 5. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:SH3 5
    PFAM PF00018
    SuperFamily 48065
    CATH 1.20.900.10
    DH. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:DH
    PFAM PF00621
    PH. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:PH
    C2. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:C2


NESG targets
    HR3646A
    HR3646E
    HR3646B
    HR3646C
    HR3646G
    HR3646D
    HR3646F

HR3646

       PDB seq homology



Constructs and Most Advanced Status
   
HR3646E-Av6HT.*

   
HR3646E-14.*

   
HR3646E-AVMBPB2.*

   
HR3646E-AvMBPB2.*

   
HR3646E-AvSUMO.*

   
HR3646E-SGCAv.*

   
HR3646E-15.*

   
HR3646G-1148-1233-14.*

   
HR3646G-1153-1228-14.*

   
HR3646F-1584-1721-14.*

   
HR3646F-1589-1721-14.*



most recent record
11 years, 21 days ago --     target created

2006-09-06    target: HR3646B     work stopped (2010-06-30; End of PSI-2)