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HR4435   (SATB1)

5 targets assoicated with this target.
HR4435Achild(1-352)selected
HR4435Cchild(368-452)soluble construct with excellent ES score
HR4435Dchild(53-254)purified
HR4435Echild(53-178)HSQC collected
HR4435Bchild(193-245)NMR and X-Ray structures

database refs UniProt: Q01826 (SATB1_HUMAN)   |   HUGO: SATB1   |   NCBI gene: 6304   |   refSeq: NP_001124482.1; NP_001182399.1; NP_002962.1
status selected
properties length: 763 aa   |   mass: 85.96 kD   |   pI: 6.10   |   ext: 66810   |   organism: Homo sapiens
classes Biomedical: Cancer BioNet T1 (Rutgers), Biomedical: Cancer BioNet T3 (Rutgers), Biomedical: Cancer BioNet, BioMedical, Biomedical: Transcription Factor, PSI-Biology
projects Transcription Factor     HCPIN    
best PDB match calculating ...
informatics Dismeta report   |   Zn binding sites: no sites identified. CH type (data) CHDE type (data)
domain signaturesDNA_BIND:Homeobox details   MOTIF:Protein interaction details   DNA_BIND:CUT 2 details   SITE:Cleavage; by caspases details   47413 details   BINDING:Matrix attachment region (MAR) DNA details   1.10.260.40 details   MOTIF:Nuclear localization signal details   PF02376 details   DNA_BIND:CUT 1 details  
subsequence details   ie 100-200    
BLAST searches

Construct coverage schematic
There are no constructs associated with this target (HR4435).
However there are constructs associated with other targets associated with this target (below).

Domain and UniProt Features
    Nuclear localization signal domain_number-1
    UniProt MOTIF:Nuclear localization signal
    UniProt MOTIF:Protein interaction
    Protein interaction domain_number-1
    Cleavage; by caspases domain_number-1
    UniProt SITE:Cleavage; by caspases
    SuperFamily 47413
    CUT 1. {ECO:0000255|PROSITE- domain_number-1
    UniProt DNA_BIND:CUT 1
    PFAM PF02376
    CATH 1.10.260.40
    Binding - Matrix attachment region (MAR) DNA domain_number-1
    UniProt BINDING:Matrix attachment region (MAR) DNA
    Binding - Matrix attachment region (MAR) DNA domain_number-2
    SuperFamily 47413
    CUT 2. {ECO:0000255|PROSITE- domain_number-1
    UniProt DNA_BIND:CUT 2
    PFAM PF02376
    CATH 1.10.260.40
    Homeobox. {ECO:0000255|PROSITE- domain_number-1
    UniProt DNA_BIND:Homeobox


NESG targets
    HR4435A
    HR4435D
    HR4435E
    HR4435B
    HR4435C

HR4435

       PDB seq homology



Constructs and Most Advanced Status
   
HR4435D-53-254-15.*

   
HR4435E-53-178-15.*

   
HR4435E-56-175-15.*

   
HR4435D-56-250-15.*

   
HR4435B-174-250-14.*

   
HR4435B-174-254-14.*

   
HR4435B-179-244-14.*

   
HR4435B-179-250-14.*

   
HR4435C-368-452-TEV.*



most recent record
8 years, 18 days ago --     target created

2009-08-07    target: HR4435