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HR4714B   (UPF3A)

2 targets assoicated with this target.
HR4714parentselected
HR4714Asibling(58-154)selected

database refs UniProt: Q9H1J1 (REN3A_HUMAN)   |   HUGO: UPF3A   |   NCBI gene: 65110   |   refSeq: NP_075387.1; NP_542418.1
status NMR structure
structures 2L08 (NMR)  
properties length: 101 aa   |   mass: 11.96 kD   |   pI: 9.23   |   ext: 8940   |   organism: Homo sapiens
classes Biomedical: Cancer BioNet T1 (Rutgers), Biomedical: Cancer BioNet T3 (Rutgers), Biomedical: Cancer BioNet, BioMedical, PSI-Biology
projects HCPIN    
best PDB match calculating ...
informatics Zn binding sites: no sites identified. CH type (data) CHDE type (data)
domain signatures54928 details   PF03467 details   3.30.70.330 details  
subsequence details   ie 100-200    
BLAST searches

Construct coverage schematic
Display constructs only from this target (HR4714B).
Display constructs associated with this target (HR4714B) and all other associated targets (HR4714, HR4714A).


Domain and UniProt Features
    PFAM PF03467
    SuperFamily 54928
    CATH 3.30.70.330


NESG targets
    HR4714A
    HR4714B

HR4714

       PDB seq homology



Constructs and Most Advanced Status
   
HR4714B-58-155-14.*

   
HR4714B-62-155-14.*

   
HR4714B-70-155-14.*



most recent record
7 years, 2 days ago --     NMR structure: 2l08

2009-08-17    target: HR4714B
2009-09-25    construct: HR4714B-58-155-14.8
2009-10-12    expression [ 3, 2 ] : HR4714B-58-155-14.8-ss
2009-09-25    construct: HR4714B-62-155-14.10
2009-10-12    expression [ 3, 0 ] : HR4714B-62-155-14.10-ss
2009-09-23    construct: HR4714B-58-155-14.1
2009-10-12    expression [ 3, 2 ] : HR4714B-58-155-14.1-ss
2009-09-23    construct: HR4714B-62-155-14.3
2009-10-12    expression [ 3, 2 ] : HR4714B-62-155-14.3-ss
2009-09-23    construct: HR4714B-70-155-14.5
2009-10-12    expression [ 3, 4 ] : HR4714B-70-155-14.5-ss
2009-09-23    construct: HR4714B-70-155-14.6
2009-10-12    expression [ 3, 5 ] : HR4714B-70-155-14.6-ss
2009-10-27    expression [ 4, 5 ] : HR4714B-70-155-14.6-NC5b
2010-01-05    purification [28.2 mg]: HR4714B-70-155-14.6-NC5b-GF
2010-01-25     HR4714B.004 @ Rutgers; 0.04 ml at 0.77 mM
2010-02-02    HSQC [good]: HR4714B.004.600MHz.20C
2010-01-25     HR4714B.005 @ Rutgers; 2.4 ml at 0.77 mM
2010-03-19     HR4714B.006 @ Rutgers; 0.45 ml at 0.77 mM
2009-10-27    expression [ 4, 5 ] : HR4714B-70-155-14.6-NC5a
2009-12-09    purification [21.7 mg]: HR4714B-70-155-14.6-NC5a-Ni
    HR4714B.001 @ Rutgers; Unknown volume and concentration
2009-12-10    purification [6.5 mg]: HR4714B-70-155-14.6-NC5a-GF
2009-12-17     HR4714B.002 @ Rutgers; 0.04 ml at 0.308 mM
2010-02-08    HSQC [poor]: HR4714B.002.600MHz.20C
2009-12-17     HR4714B.003 @ Rutgers; 0.5 ml at 0.641 mM
2010-02-03    expression [ 4, 5 ] : HR4714B-70-155-14.6-NCa
2010-02-11    purification [38.1 mg]: HR4714B-70-155-14.6-NCa-GF
2010-02-17     aggregation screening [monomer,12.76 kD,80.2%|monomer,16.21 kD,10.1%]
2010-02-19     HR4714B.007 @ Rutgers; 0.3 ml at 0.816 mM
2010-02-19     hr4714b.008 @ Rutgers; 3 ml at 0.816 mM
2010-06-30     NMR structure: 2l08 (PDB)
2010-02-03    expression [ 4, 5 ] : HR4714B-70-155-14.6-NC5c
2010-02-11    purification [27.4 mg]: HR4714B-70-155-14.6-NC5c-GF
2010-02-19     HR4714B.010 @ Rutgers; 0.5 ml at 0.902 mM
2010-02-19     hr4714b.011 @ Rutgers; 1.8 ml at 0.902 mM
2010-03-01     HR4714B.009 @ UGA; 0.5 ml at 0.902 mM


Available samples:

NC samples
hr4714b.008 @ Rutgers HR4714B.007 @ Rutgers


NC5 samples
HR4714B.010 @ Rutgers HR4714B.002 @ Rutgers HR4714B.003 @ Rutgers
hr4714b.011 @ Rutgers HR4714B.004 @ Rutgers HR4714B.009 @ UGA HR4714B.006 @ Rutgers HR4714B.005 @ Rutgers
HR4714B.001 @ Rutgers