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HR4730A   (RBM39)

6 targets assoicated with this target.
HR4730Dsibling(235-530)selected
HR4730Bsibling(116-359)selected
HR4730Csibling(310-530)selected
HR4730Esibling(116-519)selected
HR4730Fsibling(414-518)HSQC collected and crystal hits
HR4730parentgood HSQC collected and crystal hits

database refs UniProt: Q14498 (RBM39_HUMAN)   |   HUGO: RBM39   |   NCBI gene: 9584   |   refSeq: NP_004893.1; NP_909122.1
status NMR structure
structures 2JRS (NMR)  
properties length: 97 aa   |   mass: 10.68 kD   |   pI: 6.14   |   ext: 2980   |   organism: Homo sapiens
classes PSI-2, Community Outreach, Biomedical: Cancer BioNet T3 (Rutgers), MEGA, Biomedical: Cancer BioNet, BioMedical, PSI-Biology
projects HCPIN    
best PDB match calculating ...
informatics Prof PHD data   |   Pxs: 0.334   |   Zn binding sites: no sites identified. CH type (data) CHDE type (data)
domain signaturesDOMAIN:RRM 2 details   54928 details   PF00076 details   3.30.70.330 details  
subsequence details   ie 100-200    
BLAST searches

Construct coverage schematic
Display constructs only from this target (HR4730A).
Display constructs associated with this target (HR4730A) and all other associated targets (HR4730, HR4730D, HR4730B, HR4730C, HR4730F, HR4730E).


Domain and UniProt Features
    CATH 3.30.70.330
    SuperFamily 54928
    RRM 1. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:RRM 1
    CATH 3.30.70.330
    SuperFamily 54928
    RRM 2. {ECO:0000255|PROSITE- domain_number-1
    UniProt DOMAIN:RRM 2
    PFAM PF00076
    PFAM PF13893
    SuperFamily 54928
    CATH 3.30.70.330
    UniProt DOMAIN:RRM 3
    RRM 3. {ECO:0000255|PROSITE- domain_number-1


NESG targets
    HR4730B
    HR4730E
    HR4730D
    HR4730A
    HR4730C
    HR4730F

HR4730

       PDB seq homology



Constructs and Most Advanced Status
   
HR4730-15.*

   
HR4730-116-359-14.*

   
HR4730-135-422-15.*

   
HR4730A-15.*

   
HR4730-235-530-15.*

   
HR4730-235-422-15.*

   
HR4730-310-530-14.*

   
HR4730F-409-523-14.*

   
HR4730F-414-518-14.*



most recent record
8 years, 13 days ago --     expression [3, 5]: HR4730A-15.3-Na; expression [4, 5]: HR4730A-15.3-LBb

2006-09-06    target: HR4730A
2006-12-01    construct: HR4730A-15.1
2006-12-06    expression [ 5, 5 ] : HR4730A-15.1-ss
2006-12-01    construct: HR4730A-15.3
2006-12-20    expression [ 5, 5 ] : HR4730A-15.3-NC5a
2007-02-13    purification [17.7 mg]: HR4730A-15.3-NC5a-GF
2006-12-06    expression [ 5, 5 ] : HR4730A-15.3-ss
2007-01-25    expression [ 4, 5 ] : HR4730A-15.3-SeMa
2007-01-30    purification [21.4 mg]: HR4730A-15.3-SeMa-GF
2007-02-20     aggregation screening [monomer,14.14 kD,98%]
2007-02-06     HR4730.007 @ HWI; 0.45 ml at 8.8 mg/mL
2007-02-06     HR4730.008 @ Rutgers; 1.5 ml at 8.8 mg/mL
2007-02-14    expression [ 5, 5 ] : HR4730A-15.3-NC5b
2007-02-20    purification [30.4 mg]: HR4730A-15.3-NC5b-GF
    HR4730.012 @ Rutgers; 6 ml at 1.1 mM
2007-02-14    expression [ 5, 5 ] : HR4730A-15.3-NCa
2007-02-20    purification [31.5 mg]: HR4730A-15.3-NCa-GF
2007-02-22    expression [ 4, 5 ] : HR4730A-15.3-NC5c
2007-02-27    purification [30.4 mg]: HR4730A-15.3-NC5c-GF
2007-02-22    expression [ 4, 5 ] : HR4730A-15.3-NCb
2007-02-27    purification [15.9 mg]: HR4730A-15.3-NCb-GF
2007-04-04     HR4730A.001 @ Rutgers; 1.5 ml at 1.3 mM
2007-03-05     HR4730A.002 @ Rutgers; 0.3 ml at 1.3 mM
2007-04-04     HR4730A.003 @ Rutgers; 0.3 ml at 1.3 mM
2007-06-28     NMR structure: 2jrs (PDB)
2008-07-01    expression [ 4, 5 ] : HR4730A-15.3-LBa
2008-07-16    purification [11.4 mg]: HR4730A-15.3-LBa-Ni
2008-12-09     HR4730A.006 @ Rutgers; 0.45 ml at 7.92 mg/mL
2008-07-24     HR4730A.004 @ Rutgers; 1 ml at 1 mg/mL
2008-07-24     HR4730A.005 @ Rutgers; 0.8 ml at 7.92 mg/mL
2009-04-15    expression [ 3, 5 ] : HR4730A-15.3-Na
2009-04-15    expression [ 4, 5 ] : HR4730A-15.3-LBb
2006-12-01    construct: HR4730A-15.4
2006-12-06    expression [ 5, 5 ] : HR4730A-15.4-ss


Available samples:

LB samples
HR4730A.005 @ Rutgers HR4730A.004 @ Rutgers HR4730A.006 @ Rutgers


SeMet samples
HR4730.007 @ HWI HR4730.008 @ Rutgers


NC samples
HR4730A.001 @ Rutgers HR4730A.003 @ Rutgers HR4730A.002 @ Rutgers


NC5 samples
HR4730.012 @ Rutgers