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HR5043   (COQ9)

2 targets assoicated with this target.
HR5043Bchild(210-286)expressed
HR5043Achild(210-318)expressed

database refs UniProt: O75208 (COQ9_HUMAN)   |   HUGO: COQ9   |   NCBI gene: 57017   |   refSeq: NP_064708.1
status X-Ray structure
structures 4RHP (Xray)  
properties length: 318 aa   |   mass: 35.51 kD   |   pI: 5.61   |   ext: 41940   |   organism: Homo sapiens
classes PSI-2, BIG: Rutgers, NESG-BIG-OPEN, MPP: Community Outreach, PSI-Biology
projects COQ9     PSI:Biology Partner - MPP     MPP biomedical targets     MPP nominated projects    
best PDB match calculating ...
informatics Prof PHD data   |   DISOPRED2 data   |   Pxs: 0.144   |   Zn binding sites: no sites identified. CH type (data) CHDE type (data)
domain signaturesTRANSIT:Mitochondrion (Potential) details   BIG_674 details   PF08511 details  
subsequence details   ie 100-200    
BLAST searches

Construct coverage schematic
Display constructs only from this target (HR5043).
Display constructs associated with this target (HR5043) and all other associated targets (HR5043B, HR5043A).


Domain and UniProt Features
    Transit - Mitochondrion. {ECO:0000255} domain_number-1
    UniProt TRANSIT:Mitochondrion (Potential)
    PFAM PF08511
    BIG BIG_674


NESG targets
    HR5043B
    HR5043A

HR5043

       PDB seq homology



Constructs and Most Advanced Status
   
MPP-GO.118989-1-318

   
MPP-GO.121176-45-318

   
MPP-GO.121177-46-318

   
HR5043-79-318-MBP3.*

   
HR5043-95-318-15.*

   
HR5043-95-318-Av6HT.*

   
HR5043-115-318-Av6HT.*

   
HR5043-115-318-15.*

   
HR5043A-176-318-15.*

   
HR5043A-176-318-Av6HT.*

   
HR5043B-209-288-15.*

   
HR5043B-209-288-Av6HT.*

   
HR5043B-209-318-Av6HT.*

   
HR5043B-209-318-15.*



most recent record
3 years, 9 days ago --     expression [5, 5]: HR5043-79-318-MBP3.11-SeMc

2006-08-10    target: HR5043
2011-08-19    construct: HR5043-115-318-Av6HT.1
2011-09-07    expression [ 5, 0, not tested ]: HR5043-115-318-Av6HT.1-ss
2011-08-19    construct: HR5043-115-318-Av6HT.2
2011-09-07    expression [ 5, 0, not tested ]: HR5043-115-318-Av6HT.2-ss
2011-08-19    construct: HR5043-95-318-Av6HT.3
2011-09-07    expression [ 5, 0, not tested ]: HR5043-95-318-Av6HT.3-ss
2011-08-19    construct: HR5043-95-318-Av6HT.4
2011-09-07    expression [ 5, 0, not tested ]: HR5043-95-318-Av6HT.4-ss
2012-10-05    construct: HR5043-79-318-MBP3.11
2012-10-11    expression [ 5, 5, not tested ]: HR5043-79-318-MBP3.11-ss
2012-10-24    expression [ 5, 5, not tested ]: HR5043-79-318-MBP3.11-SeMa
2012-11-06    purification [57.6 mg]: HR5043-79-318-MBP3.11-SeMa-GF
2012-11-08    purification [14.8 mg]: HR5043-79-318-MBP3.11-SeMa-TV
2012-11-14    purification [8.0 mg]: HR5043-79-318-MBP3.11-SeMa-GF2
2012-12-04     aggregation screening [dimer,51.39 kD,96.9%]
2012-11-26     HR5043.001 @ HWI; 0.45 ml at 5.46 mg/mL
2012-11-26     HR5043.002 @ Columbia; 0.65 ml at 5.46 mg/mL
2013-07-10    expression [ 4, 5, not tested ]: HR5043-79-318-MBP3.11-LBa
2013-08-12    purification [10.5 mg]: HR5043-79-318-MBP3.11-LBa-GF
2013-08-20     aggregation screening [dimer,122.9 kD,80.2%|aggregated,2120 kD,7.5%]
2013-08-15     HR5043.009 @ Rutgers; 0.65 ml at 8.89 mg/mL
2013-08-20     HR5043.008 @ Rutgers; 0.45 ml at 8.89 mg/mL
2013-08-14    purification [7.2 mg]: HR5043-79-318-MBP3.11-LBa-TV
2013-08-20     aggregation screening [dimer,52.05 kD,76.1%|pentamer,136.9 kD,14.3%|aggregated,908 kD,6.7%]
2013-08-15     HR5043.010 @ Rutgers; 0.35 ml at 4.22 mg/mL
2014-06-24    expression [ 5, 5, not tested ]: HR5043-79-318-MBP3.11-SeMb
2014-07-07    purification [0.0 mg]: HR5043-79-318-MBP3.11-SeMb-GF
2014-07-17    expression [ 5, 5, not tested ]: HR5043-79-318-MBP3.11-SeMc
2012-10-05    construct: HR5043-79-318-MBP3.12
2012-10-11    expression [ 5, 5, not tested ]: HR5043-79-318-MBP3.12-ss
2012-09-28    construct: HR5043-115-318-15.9
2012-10-15    expression [ 4, 0 ] : HR5043-115-318-15.9-ss
2012-09-28    construct: HR5043-115-318-15.10
2012-10-15    expression [ 4, 0 ] : HR5043-115-318-15.10-ss
2012-10-22    construct: HR5043-95-318-15.13
2012-12-05    expression [ 5, 2 ] : HR5043-95-318-15.13-ss
2013-02-12    expression [ 5, 4 ] : HR5043-95-318-15.13-SeMb
2013-03-04    purification [27.2 mg]: HR5043-95-318-15.13-SeMb-GF
2013-03-12     aggregation screening [trimer,70.42 kD,91.9%|aggregated,12260 kD,2.9%]
2013-03-06     HR5043.003 @ HWI; 0.45 ml at 10.29 mg/mL
2013-03-06     HR5043.004 @ Columbia; 2 ml at 10.29 mg/mL
    X-Ray structure: 4rhp (PDB)
2013-03-06     HR5043.005 @ Rutgers; 0.2 ml at 10.29 mg/mL
2013-02-12    expression [ 0, 0 ] : HR5043-95-318-15.13-SeMa
2012-10-22    construct: HR5043-95-318-15.14
2012-12-05    expression [ 0, 0 ] : HR5043-95-318-15.14-ss
2014-06-12    expression [ 4, 2 ] : HR5043-95-318-15.1-SeMa
2014-06-12    expression [ 5, 1 ] : HR5043-95-318-15.1-SeMb
2013-06-20     HR5043.006 @ Rutgers; 0.003 ml at 0.05 mg/mL
2013-06-20     HR5043.007 @ Rutgers; 0.003 ml at 0.05 mg/mL


Available samples:

LB samples
HR5043.009 @ Rutgers HR5043.010 @ Rutgers HR5043.008 @ Rutgers


SeMet samples
HR5043.003 @ HWI HR5043.001 @ HWI
HR5043.004 @ Columbia HR5043.005 @ Rutgers HR5043.002 @ Columbia


E-mail communications associated with this target:

  2012-12-05
  2012-12-06
  2012-12-06
  2013-03-13
  2013-03-14
  2013-03-20
  2013-06-26
  2013-06-26