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HR6741A   (AFG3L2)

3 targets assoicated with this target.
HR6741parentselected
HR6741Csibling(287-675)purified
HR6741Bsibling(279-758)aggregation screening

database refs UniProt: Q9Y4W6 (AFG32_HUMAN)   |   HUGO: AFG3L2   |   NCBI gene: 10939   |   refSeq: NP_006787.2
status NMR structure
structures 2LNA (NMR)  
properties length: 89 aa   |   mass: 10.42 kD   |   pI: 8.27   |   ext: 20970   |   organism: Homo sapiens
classes MPP: Biomedical, MPP: Community Outreach, PSI-Biology
projects AFG3L2     MPP biomedical targets     MPP nominated projects     PSI:Biology Partner - MPP    
best PDB match calculating ...
informatics Dismeta report   |   Zn binding sites: no sites identified. CH type (data) CHDE type (data)
domain signaturesPF06480 details  
subsequence details   ie 100-200    
BLAST searches

Construct coverage schematic
Display constructs only from this target (HR6741A).
Display constructs associated with this target (HR6741A) and all other associated targets (HR6741, HR6741C, HR6741B).


Domain and UniProt Features
    Helical. {ECO:0000255} domain_number-1
    UniProt TRANSMEM:Helical; (Potential)
    Helical. {ECO:0000255} domain_number-2
    CATH 3.40.50.300
    SuperFamily 52540
    ATP. {ECO:0000255} domain_number-1
    UniProt NP_BIND:ATP (Potential)
    PFAM PF01434
    Zinc; catalytic domain_number-1
    {ECO:0000250|UniProtKB:Q9WZ49} domain_number-1
    UniProt ACT_SITE:By similarity
    Zinc; catalytic domain_number-2
    UniProt METAL:Zinc; catalytic (By similarity)
    Zinc; catalytic domain_number-3


NESG targets
    HR6741A
    HR6741B
    HR6741C

HR6741

       PDB seq homology



Constructs and Most Advanced Status
   
HR6741A-15.*

   
HR6741B-286-756-15.*

   
HR6741C-290-689-15.*

   
HR6741B-290-756-15.*

   
HR6741C-290-676-15.*



most recent record
5 years, 10 days ago --     NMR structure: 2lna

2011-02-09    target: HR6741A
2011-03-02    construct: HR6741A-15.1
2011-08-19    expression [ 5, 5 ] : HR6741A-15.1-NCa
2011-09-27    purification [58.1 mg]: HR6741A-15.1-NCa-GF
2011-08-24     HR6741A.001 @ Miami; 0.3 ml at 0.7 mM
2011-12-20     NMR structure: 2lna (PDB)
2011-08-19    expression [ 5, 5 ] : HR6741A-15.1-NC5a
2011-09-27    purification [53.9 mg]: HR6741A-15.1-NC5a-GF
2011-08-24     HR6741A.002 @ Miami; 1 ml at 0.98 mM


Available samples:

NC samples
HR6741A.001 @ Miami


NC5 samples
HR6741A.002 @ Miami