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HR7784A   (ZFP91)

2 targets assoicated with this target.
HR7784parentselected
HR7784Bsibling(313-453)purified

database refs UniProt: Q96JP5 (ZFP91_HUMAN)   |   HUGO: ZFP91   |   NCBI gene: 80829   |   refSeq: NP_001183980.1; NP_444251.1
status NMR structure
structures 2M9A (NMR)  
properties length: 53 aa   |   mass: 6.28 kD   |   pI: 9.20   |   ext: 8480   |   organism: Homo sapiens
classes Biomedical: Cancer BioNet, Biomedical: Transcription Factor, PSI-Biology
projects HCPIN     Transcription Factor    
best PDB match calculating ...
informatics Dismeta report   |   Zn binding sites: CH type found (data) CHDE type found (data)
domain signaturesZN_FING:C2H2-type 4 details   PF13465 details   PF00096 details   3.30.160.60 details   ZN_FING:C2H2-type 3 details   57667 details  
subsequence details   ie 100-200    
BLAST searches

Construct coverage schematic
Display constructs only from this target (HR7784A).
Display constructs associated with this target (HR7784A) and all other associated targets (HR7784, HR7784B).


Domain and UniProt Features
    Zinc finger - C2H2-type 1. {ECO:0000255|PROSITE- domain_number-1
    UniProt ZN_FING:C2H2-type 1
    SuperFamily 57667
    CATH 3.30.160.60
    Zinc finger - C2H2-type 2. {ECO:0000255|PROSITE- domain_number-1
    UniProt ZN_FING:C2H2-type 2
    SuperFamily 57667
    CATH 3.30.160.60
    SuperFamily 57667
    Zinc finger - C2H2-type 3. {ECO:0000255|PROSITE- domain_number-1
    UniProt ZN_FING:C2H2-type 3
    PFAM PF00096
    SuperFamily 57667
    CATH 3.30.160.60
    PFAM PF13465
    UniProt ZN_FING:C2H2-type 4
    Zinc finger - C2H2-type 4. {ECO:0000255|PROSITE- domain_number-1
    PFAM PF13465
    UniProt ZN_FING:C2H2-type 5
    Zinc finger - C2H2-type 5. {ECO:0000255|PROSITE- domain_number-1


NESG targets
    HR7784B
    HR7784A

HR7784

       PDB seq homology



Constructs and Most Advanced Status
   
HR7784B-313-454-Av6HT.*

   
HR7784A-364-427-15.*

   
HR7784A-370-456-15.*

   
HR7784A-370-422-15.*



most recent record
4 years, 2 days ago --     NMR structure: 2m9a

2011-03-16    target: HR7784A
2011-05-04    construct: HR7784A-364-427-15.1
2011-05-25    expression [ 3, 4 ] : HR7784A-364-427-15.1-ss
2011-05-04    construct: HR7784A-364-427-15.2
2011-05-25    expression [ 3, 5 ] : HR7784A-364-427-15.2-ss
2011-08-30    expression [ 5, 3 ] : HR7784A-364-427-15.2-SeMb
2011-09-06    purification [0.0 mg]: HR7784A-364-427-15.2-SeMb-GF
2011-08-30    expression [ 5, 3 ] : HR7784A-364-427-15.2-SeMa
2011-09-06    purification [0.0 mg]: HR7784A-364-427-15.2-SeMa-GF
2011-08-29    expression [ 5, 3 ] : HR7784A-364-427-15.2-NC5a
2011-11-15    purification [1.8 mg]: HR7784A-364-427-15.2-NC5a-Ni
2011-11-16    purification [0.9 mg]: HR7784A-364-427-15.2-NC5a-GF
2011-12-06     HR7784A.004 @ Rutgers; 0.04 ml at 0.392 mM
2011-12-12    HSQC [good]: HR7784A.004.600MHz.20C
2011-12-06     HR7784A.005 @ Rutgers; 0.3 ml at 0.392 mM
2011-08-29    expression [ 5, 4 ] : HR7784A-364-427-15.2-NC5c
2011-08-29    expression [ 5, 4 ] : HR7784A-364-427-15.2-NC5b
2011-11-15    purification [1.8 mg]: HR7784A-364-427-15.2-NC5b-Ni
2011-11-16    purification [0.9 mg]: HR7784A-364-427-15.2-NC5b-GF
2011-05-04    construct: HR7784A-370-422-15.3
2011-05-25    expression [ 2, 5 ] : HR7784A-370-422-15.3-ss
2011-05-04    construct: HR7784A-370-422-15.4
2011-05-25    expression [ 2, 4 ] : HR7784A-370-422-15.4-ss
2011-05-04    construct: HR7784A-370-456-15.5
2011-05-25    expression [ 3, 5 ] : HR7784A-370-456-15.5-ss
2011-08-29    expression [ 5, 4 ] : HR7784A-370-456-15.5-SeMa
2011-09-06    purification [24.0 mg]: HR7784A-370-456-15.5-SeMa-GF
2011-09-13     aggregation screening [#VALUE!,. kD,0%]
2011-09-19     HR7784A.001 @ Rutgers; 0.35 ml at 6.2 mg/mL
2011-08-29    expression [ 5, 4 ] : HR7784A-370-456-15.5-SeMb
2011-09-06    purification [24.0 mg]: HR7784A-370-456-15.5-SeMb-GF
2011-08-29    expression [ 5, 4 ] : HR7784A-370-456-15.5-NC5a
2011-11-05    purification [5.8 mg]: HR7784A-370-456-15.5-NC5a-Ni
2011-11-06    purification [0.4 mg]: HR7784A-370-456-15.5-NC5a-GF
2011-12-07     aggregation screening [#VALUE!,. kD,0%]
2011-11-14     HR7784A.002 @ Rutgers; 0.04 ml at 0.308 mM
2011-11-21    HSQC [good]: HR7784A.002.600MHz.20C
2011-11-14     HR7784A.003 @ Rutgers; 0.08 ml at 0.308 mM
2011-08-29    expression [ 5, 4 ] : HR7784A-370-456-15.5-NC5b
2012-01-04    purification [67.1 mg]: HR7784A-370-456-15.5-NC5b-Ni
2012-01-04    purification [26.8 mg]: HR7784A-370-456-15.5-NC5b-GF
2012-01-23     HR7784A.008 @ UGA; 0.5 ml at 0.295 mM
2012-01-25    HSQC [good]: HR7784A.008.600MHz.20C
2012-01-23     HR7784A.009 @ Rutgers; 0.05 ml at 0.295 mM
2011-08-29    expression [ 5, 5 ] : HR7784A-370-456-15.5-NC5c
2012-01-04    purification [67.1 mg]: HR7784A-370-456-15.5-NC5c-Ni
2012-01-04    purification [26.8 mg]: HR7784A-370-456-15.5-NC5c-GF
2011-12-21    expression [ 5, 4 ] : HR7784A-370-456-15.5-NCa
2012-01-04    purification [42.4 mg]: HR7784A-370-456-15.5-NCa-Ni
2012-01-04    purification [14.9 mg]: HR7784A-370-456-15.5-NCa-GF
2012-01-23     hr7784a.006 @ UGA; 0.3 ml at 0.236 mM
2012-01-25    HSQC [good]: HR7784A.006.600MHz.20C
2012-01-23     HR7784A.007 @ Rutgers; 0.1 ml at 0.23 mM
2012-01-04    expression [ 5, 4 ] : HR7784A-370-456-15.5-NC5d
2012-06-07    purification [43.3 mg]: HR7784A-370-456-15.5-NC5d-Ni
2012-06-07    purification [29.8 mg]: HR7784A-370-456-15.5-NC5d-GF
2012-07-06     HR7784A.013 @ Rutgers; 0.5 ml at 0.66 mM
2012-07-06     HR7784A.012 @ UGA; 0.5 ml at 0.66 mM
2012-05-30    expression [ 5, 5 ] : HR7784A-370-456-15.5-NCb
2012-06-07    purification [66.1 mg]: HR7784A-370-456-15.5-NCb-Ni
2012-06-07    purification [65.9 mg]: HR7784A-370-456-15.5-NCb-GF
2012-07-06     HR7784A.011 @ Rutgers; 0.7 ml at 1.17 mM
2012-07-06     HR7784A.010 @ UGA; 0.3 ml at 1.17 mM
2013-07-24     NMR structure: 2m9a (PDB)
2013-03-14    expression [ 5, 3 ] : HR7784A-370-456-15.5-LBa
2013-05-14    purification [18.0 mg]: HR7784A-370-456-15.5-LBa-Ni
2013-05-16     HR7784A.014 @ CDI Mayaguez, PR; 0.75 ml at 5.98 mg/mL
2013-05-16     HR7784A.015 @ JHU/CDI Baltimore, MD; 1 ml at 0.226 mg/mL
2011-05-04    construct: HR7784A-370-456-15.6
2011-05-25    expression [ 3, 4 ] : HR7784A-370-456-15.6-ss


Available samples:

LB samples
HR7784A.014 @ CDI Mayaguez, PR HR7784A.015 @ JHU/CDI Baltimore, MD


SeMet samples
HR7784A.001 @ Rutgers


NC samples
HR7784A.011 @ Rutgers HR7784A.010 @ UGA
HR7784A.007 @ Rutgers hr7784a.006 @ UGA


NC5 samples
HR7784A.012 @ UGA HR7784A.008 @ UGA HR7784A.013 @ Rutgers
HR7784A.009 @ Rutgers HR7784A.003 @ Rutgers HR7784A.002 @ Rutgers HR7784A.005 @ Rutgers HR7784A.004 @ Rutgers


E-mail communications associated with this target:

  2012-07-12
  2012-07-12
  2013-05-30
  2013-05-30
  2013-05-30
  2013-05-30
  2013-05-30
  2013-05-30
  2013-06-05
  2013-06-05