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OR117   (BH25 (N42Y, N199F, F264Y, G311M))

database refs UniProt: Unknown_4984 (Unknown_4984)
status X-Ray structure    work stopped (2013-07-25; target work stopped by D. Baker)
structures 4ILS (Xray)  
properties length: 390 aa   |   mass: 43.76 kD   |   pI: 6.40   |   ext: 59360   |   organism: Other
classes Community Outreach, D. Baker, PSI-Biology
projects MBH enzyme design     Community Outreach     D Baker projects     Design projects    
best PDB match calculating ...
informatics Zn binding sites: no sites identified. CH type (data) CHDE type (data)
domain signatures3.20.20.10 details   51419 details   PF01168 details  
subsequence details   ie 100-200    
BLAST searches

Construct coverage schematic

Domain and UniProt Features
    SuperFamily 51419
    PFAM PF01168
    CATH 3.20.20.10

OR117

       PDB seq homology



Constructs and Most Advanced Status
   
OR117-29.*



most recent record
4 years, 26 days ago --     aggregation screening [dimer,80.55 kD,98.6%]

2011-05-05    target: OR117     work stopped (2013-07-25; target work stopped by D. Baker)
2011-05-10    construct: OR117-29.1
2011-05-17    expression [ 5, 3 ] : OR117-29.1-SeM-R1
2011-06-07    purification [12.0 mg]: OR117-29.1-SeM-R1-GF
2011-06-14     aggregation screening [dimer,80.44 kD,99.1%]
2011-06-09     OR117.001 @ Columbia; 0.6 ml at 7.37 mg/mL
2012-12-31     X-Ray structure: 4ILS (PDB)
2011-06-09     OR117.002 @ HWI; 0.45 ml at 7.37 mg/mL
2013-01-29    expression [ 5, 3 ] : OR117-29.1-SeM-R2
2013-03-19    purification [7.2 mg]: OR117-29.1-SeM-R2-GF
2013-04-02     aggregation screening [dimer,80.55 kD,98.6%]
2013-03-28     OR117.003 @ Columbia; 0.95 ml at 8.32 mg/mL


Available samples:

SeMet samples
OR117.003 @ Columbia OR117.002 @ HWI OR117.001 @ Columbia


E-mail communications associated with this target:

  2013-04-03
  2013-04-03